Samantha Murphy finished with a game-high and school record 49 points for the Antelopes, who rallied from 18 down in the second half to send the Tritons to their third consecutive loss to open the season.
GCU was one of three squads to finish with a 2-1 record at the Disney Classic, claiming second place behind Alaska Anchorage based on point differential. UAA won the tournament title despite a 79-73 double overtime loss to Texas Woman's University in the first game of the day.
TWU finished third, while UCSD finished fourth at 0-3.
Carlisle, who was just 6-for-27 in UCSD's first two games in Anaheim, bounced back in a big way on Sunday, finishing 16-of-29 from the field and 4-of-10 from the three-point line. She was a perfect 10-for-10 at the free throw line and also dished out a game-high seven assists.
Osga was 8-of-16 from the floor en route to her second 20-point effort of the weekend. The sophomore guard hit all four of her three-point tries and finished with six rebounds and three assists.
Lauren Freidenberg posted her second straight double-double, finishing with 17 points on 8-of-14 shooting to go with 14 rebounds. Erin Grady tallied 12 points and nine boards and Daisy Feder added 11 points, as all five Triton starters reached double figures.
Murphy was as impressive as anyone, racking up 49 points on 13-of-23 shooting, before fouling out with 2:33 remaining in the first overtime period. The reigning Pacific West Conference Player of the Year finished 5-of-9 from behind the arc and 18-of-19 at the free throw line.
Jallisa Butler scored 20 points off the bench for Grand Canyon, while Rosalyn Nelson scored 19 points and Maylinn Smith tallied 17 points and 12 boards.
Both teams shot the ball well, as GCU finished at 46% (38-82) from the field and UCSD shot just under 46% (39-85). The two squads hit a total of 17 threes in the game, while combining to shoot 83 free throws.
"We definitely got better tonight," fourth-year head coach Charity Elliott said. "We played extremely well, we battled to whole game and that was two teams that just did some miraculous things. If there was another minute, who knows, we might have come out on top."
The Tritons led by as many as 17 in the first half and held a 68-50 advantage with eight minutes left in the second, but the Antelopes would outscore UCSD 32-14 from that point on, tying the game at 82 at the end of regulation. Murphy hit two threes inside the final 1:07 and then sank three free throws to tie it with 14 seconds left after getting fouled on an attempt from behind the arc.
Carlisle hit a jumper with 1:37 remaining in the first overtime to give the Tritons a 92-91 lead and then sank two free throws to make it 96-93 in favor of UCSD with 18 seconds to play. Smith answered with a bucket on the other end for GCU, but Osga made two at the line to push the lead back to three, 98-95, with just six seconds on the clock.
Just when it looked like the Tritons had put the Antelopes away, Nelson banked in a running three from the right side of the circle and forced a second overtime with the score tied at 98.
Neither squad grabbed more than a two point lead in the second extra period until Butler scored in the paint and Kristi Girdley made one of two at the foul line to give GCU a 109-106 cushion with 16 seconds left. Feder was then fouled on her ensuing three-point attempt and calmly knocked down all three free throws to tie the game once more and force a third overtime.
The Antelopes took a 113-110 lead on a layup by Smith three minutes into the third OT, but Carlisle answered to bring the Tritons to within one. Smith scored again to push it to 115-112 and the Carlisle found Grady with a nice pass to make it a one-point game once more.
Smith was fouled and hit two free throws to give GCU a 117-114 edge with 14 seconds on the clock and it became a free throw shooting contest from there, as the Antelopes wisely prevented the Tritons from getting a look at a three.
Smith hit one of two with eight seconds remaining, giving Grand Canyon a two-point edge and Carlisle's desperation three missed the mark, as the Antelopes finally emerged as the victor, 120-118.
Carlisle scored 19 of her points after regulation, while Smith scored 11 points for GCU, taking over once Murphy fouled out.
Murphy was named the Disney Classic MVP after setting tournament records for points in a single game and for the tournament, while Carlisle earned a spot on the all-tournament team for her performance.
The Tritons will now travel to Seattle to take part in the Seattle Pacific Sodexo Classic next weekend. UCSD will face Western Washington to open the tournament on Friday, before squaring off with host SPU on Saturday.
2010 Disney West Coast Tip Off Classic All-Tournament Team
Samantha Murphy - Grand Canyon (MVP)
Hanna Johansson - Alaska Anchorage
Brooke Shepherd - Texas Woman's University
Jeanee' Thompson - Texas Woman's University